Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp315 | Osteoporosis: treatment | ECTS2014

Combination therapy with ibandronate and eldecalcitol enhances bone strength without severe suppression of bone formation in aged ovariectomized rats

Sakai Sadaoki , Takeda Satoshi , Sugimoto Masanori , Shimizu Masaru , Endo Koichi

Ibandronate (IBN), a nitrogen-containing bisphosphonate, and eldecalcitol (ELD), an active vitamin D3 derivative, are used for osteoporosis treatment. Vitamin D3 often used in combination therapies, however, there are no reports on the effects of combined IBN and ELD treatment for osteoporosis.In this study, we examined the effects of combination treatment with IBN and ELD in aged ovariectomized rats. Eight-month-old Wistar-Imamichi...